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CDK2 Rabbit Polyclonal Antibody

Cat Number: AB-81213
Conjugate: Unconjugated
Size: 100 ug
Clone: POLY
Concentration: 1mg/ml
Host: Rabbit
Isotype: IgG
Immunogen: KLH conjugated Synthetic peptide corresponding to Human Cdk2
Reactivity: Human,Mouse,Rat
Applications:

Western Blot: 1:500 -1:1000
Immunohistochemistry: 1:50

Immunofluorescence: 1: 200-1: 800

Molecular Weight: 34 kDa
Purification: Affinity purification
Synonyms: Cell division protein kinase 2, p33 protein kinase, CDK2, CDKN2, CDC28, CDC2A, Cdc2 related protein kinase, p33(CDK2), MPF
Background:

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S.pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B).

Form: Liquid
Buffer: PBS with 0.02% sodium azide, 100 μg/mL BSA and 50% glycerol.
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
AB-81213-1

Western blot analysis of Cdk2 at dilution of 1: 800

AB-81213-2

Immunohistochemistry analysis of paraffin embedded human B lymphocytoma using CDK2 ) at dilution of 1: 350

AB-81213-4

Immunohistochemistry analysis of paraffin embeddedmouse spleen using CDK2 at dilution of 1:350