Collagen Type VI Rabbit Polyclonal Antibody
| Cat Number: | AB-84738 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | collagen, type VI, alpha 1 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western Blot: 1:500-1:1000 Immunoprecipitation: 1:500-1:1000 Immunohistochemistry:1:50-1:200 Immunofluorescence: 1:20-1:200 |
| Molecular: | 140 kDa |
| Purification: | Immunogen affinity purified |
| Synonyms: | COL6A1, collagen 6A1, Collagen alpha 1(VI) chain, collagen, type VI, alpha 1, OPLL |
| Background: | Type VI Collagen is a major structural component of microfibrils. Type VI Collagen was found to be present throughout the connective tissue and in the extracellular matrix of cultured fibroblasts(PMID: 6723253). It is a heterotrimer composed of three different chains: alpha-1(VI), alpha-2(VI), and alpha-3(VI) or alpha-5(VI) or alpha-6(VI). The alpha-1(VI) chain is encoded by COL6A1 gene. Mutations in this gene result in Bethlem myopathy and Ullrich congenital muscular dystrophy. |
| Form: | Liquid |
| Buffer: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage: | Store at -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |