Top

Collagen Type VI Rabbit Polyclonal Antibody

Cat Number: AB-84738
Conjugate: Unconjugated
Size: 100 ug
Clone: POLY
Concentration: 1mg/ml
Host: Rabbit
Isotype: IgG
Immunogen: collagen, type VI, alpha 1
Reactivity: Human, Mouse, Rat
Applications:

Western Blot: 1:500-1:1000
Immunoprecipitation: 1:500-1:1000
Immunohistochemistry:1:50-1:200
Immunofluorescence: 1:20-1:200

Molecular Weight: 140 kDa
Purification: Immunogen affinity purified
Synonyms: COL6A1, collagen 6A1, Collagen alpha 1(VI) chain, collagen, type VI, alpha 1, OPLL
Background:

Type VI Collagen is a major structural component of microfibrils. Type VI Collagen was found to be present throughout the connective tissue and in the extracellular matrix of cultured fibroblasts(PMID: 6723253). It is a heterotrimer composed of three different chains: alpha-1(VI), alpha-2(VI), and alpha-3(VI) or alpha-5(VI) or alpha-6(VI). The alpha-1(VI) chain is encoded by COL6A1 gene. Mutations in this gene result in Bethlem myopathy and Ullrich congenital muscular dystrophy.

Form: Liquid
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage: Store at -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
AB-84738-1

human heart tissue were subjected to SDS PAGE followed by western blot with COL6A1 Antibody at dilution of 1:600

AB-84738-2

Immunohistochemistry of paraffin-embedded human kidney using COL6A1 antibody at dilution of 1:100

AB-84738-3

IP Result of anti-Collagen Type VI (IP: 4ug; Detection: 1:500) with mouse heart tissue lysate 8000ug.