Connective tissue growth factor (CTGF, CCN2) belongs to the CCN (CYR61, CTGF, NOV) family of secreted extracellular matrix (ECM) proteins (1). Members of this family contain four conserved cysteine-rich domains, and interact in the ECM with a diverse array of cell surface receptors, includ-ing integrins and heparin-sulfate proteoglycans (2). These interactions regulate a multitude of cellular and tissue functions, including adhesion, proliferation, migration, differentiation, senescence, angiogenesis, inflammation, and wound repair (1, 3-5). The CTGF gene is a transcriptional target of both YAP/TAZ and TGFβ-SMAD signaling pathways (6,7), and aberrant regula-tion of CTGF expression is strongly associated with pathological conditions, notably cancer and fibrosis (8, 9). CTGFRabbit pAb recognizes endogenous levels of total CTGF protein. By Western blot analysis, the antibody detects a 120 kDa protein of unknown identity in both CTGF-positive and CTGF-negative cell lines.