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CXCR1

Cat Number: AB-82066
Conjugate: Unconjugated
Size: 100 μg
Clone: POLY
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CXCR1.
Reactivity: Hu
Applications:

Western Blot: 1:500 – 1:2000
Immunohistochemistry: 1:50 – 1:200

Molecular: 70kDa
Purification: Aff.Pur.
Synonyms: CXCR1;C-C;C-C-CKR-1;CD128;CD181;CDw128a;CKR-1; CMKAR1;IL8R1;IL8RA;IL8RBA
Background:

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36

Form: Liquid
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.
AB-82066-1.jpg

Western blot analysis of extracts of various cell lines, using CXCR1
antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti- Rabbit IgG (H+L)at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in
TBST.
Detection: ECL West Pico Plus.
Exposure time: 15s.

AB-82066-2.jpg

Immunohistochemistry of paraffin embedded
rat lung using CXCR1
antibody at dilution of
1:100 (40x lens).

AB-82066-3.jpg

Immunohistochemistry of paraffin embedded mouse spleen using CXCR1 antibody at dilution of 1:100 (40x lens).

AB-82066-4.jpg

Immunohistochemistry of paraffinembedded
human colon using CXCR1
antibody at dilution of 1:100
(40x lens).