Doublecortin Rabbit Polyclonal Antibody
| Cat Number: | AB-80651 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | doublecortin |
| Reactivity: | Hu, Ms, Rt |
| Applications: | Western Blot: 1:500-1:2000 |
| Molecular Weight: | 40 kDa |
| Purification: | ≥95% as determined by SDS-PAGE |
| Synonyms: | DBCN, DC, DCX, doublecortin, Doublin, Lis X, Lissencephalin X, LISX, SCLH, XLIS |
| Background: | Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. |
| Form: | Liquid |
| Buffer: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, |
| Storage: | Store -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
human brain tissue were subjected to SDS PAGE followed by western blot with DCX antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded human testis using DCX antibody at dilution of 1:100
Immunofluorescent analysis of SH-SY5Y cells using DCX antibody at dilution of 1:50 and Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L)