EGFR / HER1 Rabbit Polyclonal Antibody
| Cat Number: | AB-81864 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1021-1210 of human EGFR |
| Reactivity: | Human,Mouse,Rat |
| Applications: | Western Blot: 1:1000 - 1:5000 mmunohistochemistry(paraffin-embedded tissues) 1:50 - 1:200 Immunofluorescence: 1:100 - 1:500 Immuncytochemistry: 1:100 - 1:500 IImmunoprecipitation: 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
| Molecular Weight: | 175kDa |
| Purification: | Aff. Pur. |
| Synonyms: | ERBB; ERRP; HER1; mENA; ERBB1; PIG61; NISBD2; EGFR |
| Background: | The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. |
| Form: | Liquid |
| Buffer: | PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
| Storage: | Store at -20°C, and avoid repeat freeze-thaw cycles. |