Frataxin
| Cat Number: | AB-83941 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 42-210 of human FXN / Frataxin |
| Reactivity: | Hu, Ms, Rt |
| Applications: | Western Blot: 1:500 -1:1000 Immunohistochemistry: 1:50 - 1:100 Immunofluorescence: 1:50 -1:100 |
| Molecular: | 14kDa |
| Purification: | Aff. Pur. |
| Synonyms: | FXN; CyaY; FA; FARR; FRDA; X25; frataxin |
| Background: | This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. |
| Form: | Liquid |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C, and avoid repeat freeze-thaw cycles. |