Glutamate Transporter GLIA (GLAST /EAAT1) Rabbit Polyclonal Antibody
| Cat Number: | AB-82224 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide corresponding to a sequence at the Cterminus of human EAAT1(519-537aa MKKPYQLIAQDNETEKPID), different from the related rat and mouse sequences by three amino acids. |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blot 0.1-0.5μg/ml Immunohistochemistry(Paraffin-embedded Section): 0.5-1μg/ml Immunohistochemistry(Frozen-Section): 0.5-1μg/ml |
| Purification: | Immunogen affinity purified |
| Background: | Solute carrier family 1(glial high-affinity glutamate transporter), member 3, also known as SLC1A3,EAAT1 or GLAST, is a protein that in humans is encoded by the SLC1A3 gene. This gene is a member of high affinity glutamate transporter family. SLC1A3 is mapped to chromosome 5p13.2 by fluorescence in situ hybridization(FISH). This gene transports L-glutamate and also L- and D- aspartate. It is essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. This gene acts as a symport by cotransporting sodium. |
| Form: | Liquid |
| Buffer: | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4,0.05mg Thimerosal, 0.05mg NaN3. |
| Storage: | At -20 ̊C for one year. It can also be aliquotted and stored frozen at -20 ̊C for a longer time. Avoid repeated freezing and thawing. |