Glutamate Transporter GLIA (GLAST /EAAT1) Rabbit Polyclonal Antibody

Cat Number: AB-82224
Conjugate: Unconjugated
Size: 100 ug
Clone: POLY
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: A synthetic peptide corresponding to a sequence at the Cterminus of human EAAT1(519-537aa MKKPYQLIAQDNETEKPID), different from the related rat and mouse sequences by three amino acids.
Reactivity: Human, Mouse, Rat

Western blot 0.1-0.5μg/ml
Immunohistochemistry(Paraffin-embedded Section): 0.5-1μg/ml
Immunohistochemistry(Frozen-Section): 0.5-1μg/ml

Purification: Immunogen affinity purified

Solute carrier family 1(glial high-affinity glutamate transporter), member 3, also known as SLC1A3,EAAT1 or GLAST, is a protein that in humans is encoded by the SLC1A3 gene. This gene is a member of high affinity glutamate transporter family. SLC1A3 is mapped to chromosome 5p13.2 by fluorescence in situ hybridization(FISH). This gene transports L-glutamate and also L- and D- aspartate. It is essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. This gene acts as a symport by cotransporting sodium.

Form: Liquid
Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4,0.05mg Thimerosal, 0.05mg NaN3.
Storage: At -20 ̊C for one year. It can also be aliquotted and stored frozen at -20 ̊C for a longer time. Avoid repeated freezing and thawing.

Anti-EAAT1 antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: Mouse Brain Tissue Lysate


Anti-EAAT1 antibody, IHC(P) IHC(P): Rat Brain Tissue