Top

IGF1R Rabbit Polyclonal Antibody

Cat Number: AB-81364
Conjugate: Unconjugated
Size: 100μg
Clone: POLY
Concentration: 1mg/ml
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1201-1367 of human IGF1R.
Reactivity: Human,Mouse,Rat
Applications: Western Blot: 1:1000 - 1:5000
Molecular Weight: 100kDa
Purification: Affinity purification
Synonyms: IGFR; CD221; IGFIR; JTK13; 1R
Background:

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Form: Liquid
Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Storage: At 4°C for one month. Or store frozen at -20°C for a longer time. Avoid freezing and thawing.