Integrin b3 / CD61
| Cat Number: | AB-81992 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μg |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 609-788 of human ITGB3 |
| Reactivity: | Hu, Ms, Rt |
| Applications: | Western Blot: 1:1000 |
| Molecular Weight: | 112kDa |
| Purification: | Aff. Pur. |
| Synonyms: | ITGB3; BDPLT16; BDPLT2; CD61; GP3A; GPIIIa; GT; integrin beta-3 |
| Background: | The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signaling. |
| Form: | Liquid |
| Buffer: | PBS with 0.02% sodium azide,0.05% BSA,50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles. |
Western blot analysis of extracts of various cell lines, using ITGB3 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL West Pico Plus.
Exposure time: 10s.