Top

Integrin b3 / CD61

Cat Number: AB-81992
Conjugate: Unconjugated
Size: 100μg
Clone: POLY
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 609-788 of human ITGB3
Reactivity: Hu, Ms, Rt
Applications:

Western Blot: 1:1000

Molecular: 112kDa
Purification: Aff. Pur.
Synonyms: ITGB3; BDPLT16; BDPLT2; CD61; GP3A; GPIIIa; GT; integrin beta-3
Background:

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signaling.

Form: Liquid
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol, pH7.3
Storage: Store at -20℃. Avoid freeze / thaw cycles.
AB-81992-1.jpg

Western blot analysis of extracts of various cell lines, using ITGB3 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL West Pico Plus.
Exposure time: 10s.