KD-Validated PPT1 Mouse Monoclonal Antibody
| Cat Number: | MABN00047 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Host: | Mouse |
| Isotype: | Mouse IgG2b |
| Immunogen: | Recombinant protein of human PPT1 |
| Reactivity: | Human |
| Applications: | WB 1:500-1:2,500 |
| Molecular: | Calculated MW: 34.2kDa |
| Purification: | Affinity purification |
| Synonyms: | PPT1; Palmitoyl-Protein Thioesterase 1; CLN1; INCL; PPT; Palmitoyl-Protein Hydrolase 1; EC 3.1.2.22; Ceroid-Palmitoyl-Palmitoyl-Protein Thioesterase 1; Ceroid-Lipofuscinosis, Neuronal 1, Infantile; PPT-1 |
| Background: | The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2008] |
| Form: | Liquid |
| Buffer: | Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide. |
| Storage: | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |