LRRK2
| Cat Number: | AB-82808 |
|---|---|
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 750-910 of human LRRK2 |
| Reactivity: | Hu, Ms, Rt |
| Applications: | WB 1:500 - 1:1000 IHC 1:50 – 1:200 IF 1:50 – 1:200 ICC 1:50 – 1:200 |
| Molecular: | 290 kDa |
| Purification: | Aff. Pur. |
| Synonyms: | PARK8; RIPK7; ROCO2; AURA17; DARDARIN |
| Background: | This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. |
| Form: | Liquid |
| Buffer: | PBS with 0.01% thiomersal,50% glycerol, pH7.3. |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles |