NME
| Cat Number: | AB-81311 |
|---|---|
| Size: | 100μg |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 90 to the C-terminus of human NME1 |
| Reactivity: | Hu,Ms,Rt |
| Applications: | Western Blot: 1:500 - 1:2000 Immunohistochemistry (paraffin embedded tissues): 1:50 - 1:200 Immunofluorescence: 1:50 - 1:200 |
| Molecular Weight: | 21kDa |
| Purification: | Aff. Pur. |
| Synonyms: | NME1; AWD; GAAD; NB; NBS; NDKA; NDPK-A; NDPKA; NM23; NM23-H1; nucleoside diphosphate kinase A |
| Background: | This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of ‘A’ (encoded by this gene) and ‘B’ (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Cotranscription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. |
| Form: | Liquid |
| Buffer: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles. |