PDE5A
| Cat Number: | AB-84270 |
|---|---|
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Reactivity: | Hu, Rt |
| Applications: | Western blot: 1:1000 |
| Purification: | Aff. Pur. |
| Background: | cGMP-specific phosphodiesterase type 5 is an enzyme from the phosphodiesterase class. It is found in various tissues, most prominently the corpus cavernosum and the retina. It has also been recently discovered to play a vital role in the cardiovascular system. Furthermore, PDE5A also plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This PDE5A gene is mapped to 4q26. |
| Form: | Liquid |
| Buffer: | Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
| Storage: | At -20°C for one year. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing. |
Western blot analysis of PDE5A expression in rat lungextract (lane 1) and PANC-1 whole cell lysates(lane 2).
PDE5A at 100KD was detected using rabbit anti- PDE5A Antigen Affinity purified polyclonal antibody at 0.5 μg/mL. The blot was developed using ECL West Pico Plus.
PDE5A was detected in paraffin-embedded sections of
human thyroid cancer tissues using rabbit anti- PDE5A
Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section
was developed using SABC method