PGP9.5 (7B8) Mouse Monoclonal Antibody
| Cat Number: | MABN03486 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Clone: | 7B8 |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | IgG2b |
| Immunogen: | A synthetic peptide of human PGP9.5 |
| Reactivity: | Human,Monkey |
| Applications: | WB 1:500-1:1000,ICC/IF 1:50-1:200 |
| Molecular: | 25 kDa |
| Purification: | Affinity purification |
| Synonyms: | UCHL1 / PGP9.5; UCHL1; B220; CD 45; CD45; cd45 antigen; ec3.1.3.48; GP 180; GP180; Human homolog of severe combined immunodeficiency due to PTPRC deficiency; L CA; L-CA; lca; Leukocyte common antigen; LY 5; LY5; Protein tyrosine phosphatase receptor type C; Protein tyrosine phosphatase receptor type c polypeptide; PTPRC; PTPRC_HUMAN; Receptor-type tyrosine-protein phosphatase C; SCID due to PTPRC deficiency; t200; T200 glycoprotein; T200 leukocyte common antigen. |
| Background: | PGP9.5 is a single chain transmembraneous glycoprotein which represents the low molecular weight isoform of the Leucocyte Common Antigen (LCA). Hydrolyze isopeptide bonds between the carboxy-terminal glycine of Ub and the ε-amino group of lysine on target proteins and involved in the cotranslational processing of pro-ubiquitin and ribosomal proteins translated as ubiquitin fusions. |
| Form: | liquid |
| Buffer: | Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Western blot analysis of UCHL1 / PGP9.5 in U251, IMR32, Raji and COS7 lysates using UCHL1 / PGP9.5 antibody.
Immunocytochemistry analysis of PGP9.5 (7B8) in COS7 using UCHL1 / PGP9.5 antibody.