|Immunogen:||A phospho specific peptide corresponding to residues surrounding Ser142 of human CREB1.|
|Reactivity:||Hu, Ms, Rt|
IHC 1:50 – 1:100
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMPresponsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimµlation of the cAMP pathway. Alternate splicing of this gene resµlts in two transcript variants encoding different isoforms.
|Buffer:||PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
|Storage:||Store at -20℃. Avoid freeze / thaw cycles.|
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Phospho-CREB1-S142 antibody.