Phospho-Histone H2AFX-S139
Cat Number: | ABP-0099 |
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Conjugate: | Unconjugated |
Size: | 100 ug |
Clone: | Poly |
Concentration: | 1mg/ml |
Host: | Rb |
Isotype: | IgG |
Immunogen: | A synthetic phosphorylated peptide around S139 of human Histone H2AX |
Reactivity: | Hu |
Applications: | Western Blot: 1:1000 Immunohistochemistry: 1:50 Immunofluorescence: 1:50 |
Molecular Weight: | 17kDa |
Purification: | Affinity purification |
Synonyms: | H2AFX; H2A.X; H2A/X; H2AX; histone H2AX |
Background: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stemloop termination motif, and the polyA addition motif. |
Form: | liquid |
Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage: | Store at -20℃. Avoid freeze / thaw cycles. |