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Phospho-Insulin Receptor Substrate 1 (S307)

Cat Number: ABP-0431
Conjugate: Unconjugated
Size: 100 ug
Clone: Poly
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: Synthesized Phospho Peptide around the Phosphorylation site of human IRS_1(phospho Ser307)
Reactivity: Hu, Ms, Rt,Mk
Applications:

WB: 1:500 – 1:1000,

IHC-p 1:100- 1:200

 

Molecular Weight: 170kd
Purification: affinity purified
Synonyms: IRS1; Insulin receptor substrate 1; IRS-1
Background:

This gene encodes a protein which is  phosphorylated by insulin receptor tyrosine kinase  Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance

Form: liquid
Buffer: PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Storage: Store at -20°C. Avoid repeated freeze-thaw cycles.
ABP-0431-1

Western Blot analysis of 293 cells using Phospho-IRS-1(S307) Polyclonal Antibody diluted at 1:1000

APB-0431-2

Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight).

High-pressure and te mperature  Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contr0l (right) obtaned from antibody was pre-absorbed by immunogen peptide.

APB-0431-3

Immunohistochemical analysis of paraffin-embedded  Human breast cancer. Antibody was diluted at 1:100(4°overnight).

High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive Control (right) obtaned from antibody was pre-absorbed  by immunogen peptide