Phospho-PDK1 (S241)
| Cat Number: | ABP-0477 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | Poly |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding S241 of human PDK1 |
| Reactivity: | Hu, Ms, Rt |
| Applications: | Western Blot: 1:1000 |
| Molecular: | 63kDa |
| Purification: | Affinity purified |
| Background: | Phosphoinositide-dependent kinase 1 (PDPK1, PDK1) is a serine/threonine protein kinase integral to thefunction of the PI 3-K/Akt signaling pathway. PDK1 and mTORC2 both phosphorylate and activate PKB/Akt, ensuring a cellμlar response to stimμli such as growth factors and insμlin signaling. Akt is the maineffector of PDK1. |
| Form: | liquid |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles |