Phospho-Rsk 2/MAPKAP Kinase 1b (Ser227) Rabbit Monoclonal Antibody
| Cat Number: | MABN87518 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser227 of human Rsk 2/MAPKAP Kinase 1b |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:2000 |
| Molecular: | Calculated MW:84 kDa; Observed MW:84 kDa |
| Purification: | Affinity Purification |
| Synonyms: | CLS; RSK; HU-3; RSK2; MRX19; ISPK-1; p90-RSK2; pp90RSK2; MAPKAPK1B; S6K-alpha3 |
| Background: | This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq, Jul 2008] |
| Form: | Liquid |
| Buffer: | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |