Phospho-Smad3 (Ser423/Ser425) Rabbit Monoclonal Antibody
| Cat Number: | MABN87151 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser423/Ser425 of human Smad3 |
| Reactivity: | Human,Mouse |
| Applications: | WB 1:500-1:2000,IHC 1:100-1:200,ICC/IF 1:100-1:200 |
| Molecular: | Calculated MW:48 kDa; Observed MW:52 kDa |
| Purification: | Affinity Purification |
| Synonyms: | LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436 |
| Background: | The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene ‘mothers against decapentaplegic’ (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009] |
| Form: | Liquid |
| Buffer: | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |