Phospho-Src-Y416
| Cat Number: | ABP-0452 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | Poly |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding Y416 of human SRC Family |
| Reactivity: | Hu, Ms, Rt |
| Applications: | Western Blot: 1:500 – 1:1000 Immunohistochemistry: 1:50 – 1:100 |
| Molecular Weight: | 60kDa |
| Purification: | Affinity purification |
| Synonyms: | SRC; ASV; SRC1; THC6; c-SRC; p60-Src; proto-on cogene tyrosine-protein kinase Src |
| Background: | This gene is highly similar to the v-src gene of Rous sarcoma virus. This protooncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. |
| Form: | liquid |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles. |
Western blot analysis of extracts from COLO205 cells, using Phospho-SRC Family-Y416 antibody.
Immunohistochemistry of paraffinembedded human breast carcinoma tissue, using Phospho-SRC-Y416 antibody.