Top

Phospho-Src-Y416

Cat Number: ABP-0452
Conjugate: Unconjugated
Size: 100 ug
Clone: Poly
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: A phospho specific peptide corresponding to residues surrounding Y416 of human SRC Family
Reactivity: Hu, Ms, Rt
Applications:

Western Blot: 1:500 – 1:1000 Immunohistochemistry: 1:50 – 1:100

Molecular: 60kDa
Purification: Affinity purification
Synonyms: SRC; ASV; SRC1; THC6; c-SRC; p60-Src; proto-on cogene tyrosine-protein kinase Src
Background:

This gene is highly similar to the v-src gene of Rous sarcoma virus. This protooncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Form: liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.
ABP-0452-1.jpg

Western blot analysis of extracts from COLO205 cells, using Phospho-SRC Family-Y416 antibody.

ABP-0452-2.jpg

Immunohistochemistry of paraffinembedded human breast carcinoma tissue, using Phospho-SRC-Y416 antibody.