Phospho-Src (Y419) (9I12) Rabbit Monoclonal Antibody
| Cat Number: | MABN06015 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Tyr419 of human Src |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:2000,FC 1:20-1:50 |
| Molecular: | 60kDa |
| Purification: | Affinity purification |
| Synonyms: | p60-Src; c-Src; pp60c-src; Avian sarcoma virus; Proto-oncogene c-Src; SRC Oncogene; |
| Background: | Non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, plays an important role in osteoclastic bone resorption. Both the formation of a SRC-PTK2B complex, and SRC kinase activity are necessary for this function. Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. |
| Form: | Liquid |
| Buffer: | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |