Western Blot: 1:1000 Immunohistochemistry (paraffin-embedded tissues): 1:50 – 1:100 Immunofluorescence: 1:100 – 1:200

This gene is highly similar to the v-src gene of Rous sarcoma virus. This protooncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.