Phospho-Src (Y529) (9B14) Rabbit Monoclonal Antibody
| Cat Number: | MABN06016 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Tyr418 of human SRC Family |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:2000,ICC/IF 1:100-1:200,FC 1:20-1:50 |
| Molecular: | 60kDa |
| Purification: | Affinity purification |
| Synonyms: | ASV; Avian sarcoma virus; c SRC; cSrc; EC 2.7.10.2; Neuronal CSRC tyrosine specific protein kinase; Neuronal proto-oncogene tyrosine-protein kinase Src; Neuronal SRC; Oncogene SRC; p60 Src; pp60c src; pp60csrc; Proto oncogene tyrosine protein kinase Src; Proto-oncogene c-Src; Proto-oncogene tyrosine-protein kinase Src; Protooncogene SRC; Protooncogene SRC Rous sarcoma; Src; SRC Oncogene; SRC proto oncogene non receptor tyrosine kinase; SRC1; Tyrosine kinase pp60c src; Tyrosine protein kinase SRC1; v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog; V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian); |
| Background: | Non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, plays an important role in osteoclastic bone resorption. Both the formation of a SRC-PTK2B complex, and SRC kinase activity are necessary for this function. Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |