PINK1
| Cat Number: | AB-84045 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 282-581 of human PINK1 |
| Reactivity: | Hu, Ms, Rt |
| Applications: | IF 1:50 – 1:200 |
| Molecular Weight: | 46KD, 60KD |
| Purification: | Aff. Pur. |
| Synonyms: | PINK1; BRPK; PARK6; PTEN induced putative kinase 1 |
| Background: | This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. |
| Form: | Liquid |
| Buffer: | Liquid in PBS containing 0.02% sodium azide, 50% glycerol, Ph7.3. |
| Storage: | At +4°C for short term. For longer term store at -20°C, avoid repeat freeze-thaw cycles |
Immunofluorescence analysis of U-2 OS cells using PINK1 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of C6 cells (RAT) using PINK1 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of NIH-3T3 mouse embryo fibroblast cell using PINK1 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.