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PINK1

Cat Number: AB-84045
Conjugate: Unconjugated
Size: 100 ug
Clone: POLY
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 282-581 of human PINK1
Reactivity: Hu, Ms, Rt
Applications:

IF 1:50 – 1:200

Molecular: 46KD, 60KD
Purification: Aff. Pur.
Synonyms: PINK1; BRPK; PARK6; PTEN induced putative kinase 1
Background:

This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.

Form: Liquid
Buffer: Liquid in PBS containing 0.02% sodium azide, 50% glycerol, Ph7.3.
Storage: At +4°C for short term. For longer term store at -20°C, avoid repeat freeze-thaw cycles
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Immunofluorescence analysis of U-2 OS cells using PINK1 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

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Immunofluorescence analysis of C6 cells (RAT) using PINK1 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

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Immunofluorescence analysis of NIH-3T3 mouse embryo fibroblast cell using PINK1 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.