PROX1
Cat Number: | AB-84319 |
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Size: | 100ug |
Clone: | POLY |
Concentration: | 1mg/ml |
Host: | Rb |
Isotype: | IgG |
Immunogen: | prosperohomeobox 1 |
Reactivity: | Hu, Ms, Rt |
Applications: | Western Blot: 1:500-1:2000 |
Molecular Weight: | 90kDa |
Purification: | Aff. Pur. |
Synonyms: | prospero homeobox 1, Prospero homeobox protein 1, PROX 1, PROX1 |
Background: | Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs.Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system.Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3. |
Form: | Liquid |
Buffer: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 |
Storage: | T -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
human liver tissue were subjected to SDS PAGE followed by western blot with (PROX1 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human lymphoma using (PROX1 antibody) at dilution of 1:50
Immunofluorescent analysis of HepG2 cells using (PROX1 Antibody) at dilution of 1:100.