Cat Number: AB-84319
Size: 100ug
Clone: POLY
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: prosperohomeobox 1
Reactivity: Hu, Ms, Rt

Western Blot: 1:500-1:2000
Immunohistochemistry: 1:20-1:200
Immunofluorescence: 1:20-1:200

Molecular: 90kDa
Purification: Aff. Pur.
Synonyms: prospero homeobox 1, Prospero homeobox protein 1, PROX 1, PROX1

Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs.Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system.Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.

Form: Liquid
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Storage: T -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

human liver tissue were subjected to SDS PAGE followed by western blot with (PROX1 antibody) at dilution of 1:500


Immunohistochemistry of paraffin-embedded human lymphoma using (PROX1 antibody) at dilution of 1:50


Immunofluorescent analysis of HepG2 cells using (PROX1 Antibody) at dilution of 1:100.