S-100 beta
| Cat Number: | MAB-94448 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | 9A11B9 |
| Concentration: | 1mg/ml |
| Host: | Ms |
| Isotype: | IgG1 |
| Immunogen: | Purified recombinant fragment of S-100 beta expressed in E. Coli. |
| Reactivity: | Hu |
| Applications: | Western Blot: 1:500-1:2000 |
| Purification: | Aff. Pur. |
| Synonyms: | Protein S100-B S-100 protein beta chain S-100 protein subunit beta S100 calcium-binding protein B |
| Background: | Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity. |
| Form: | Liquid |
| Buffer: | Ascitic fluid containing 0.03% sodium azide |
| Storage: | Store at -20°C, and avoid repeat freeze-thaw cycles. |
Western Blot (WB) analysis using S-100 beta Monoclonal Antibody against full-length S-100 beta recombinant protein.
Immunohistochemistry (IHC) analysis of paraffin-embedded Human Brain, cerebellun with DAB staining using S-100 beta Monoclonal Antibody.