SGPL1
| Cat Number: | AB-83611 |
|---|---|
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C-terminal region of Human SGPL1 |
| Reactivity: | Hu, Ms, Rt |
| Applications: | Western Blot: 1:500 – 1:2000 |
| Molecular Weight: | 63524 |
| Purification: | Aff. Pur. |
| Background: | SGPL1 (Sphingosine-1-Phosphate Lyase 1) is a Protein Coding gene. Diseases associated with SGPL1 include Congenital Adrenal Insufficiency. Among its related pathways are Sphingolipid metabolism (which is part of Lipid metabolism) and Sphingolipid signaling pathway. Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. |
| Form: | Liquid |
| Buffer: | Purified antibody supplied in 1x PBS buffer with 0.02% sodium azide, 50% glycerol, pH 7.3. |
| Storage: | At -20°C for one year. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing. |
Western blot analysis of extracts of various cell lines using
Secondary Antibody: Goat anti- Rabbit Anti- IgG (H+L) at 1:10,000
Affinity purified polyclonal SGLP1 antibody at 1:1,000
Lysate/protein: 25ug/lane
Blocking buffer: 3% not fat dry milk in TBST.
The blot was developed using chemiluminescence method (ECL West Pico)
Exposure: 120’’