SHP-2 Rabbit Polyclonal Antibody
| Cat Number: | AB-84763 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human SHP-2. AA range:546-595 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western Blot: 1/500 – 1/2000 |
| Molecular Weight: | 72kD |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatograp |
| Synonyms: | PTPN11; PTP2C; SHPTP2; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3 |
| Background: | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs. are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the |
| Form: | Liquid |
| Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage: | Store at -20°C. Avoid repeated freeze-thaw cycles. |
Western Blot analysis of various cells using SH-PTP2 Polyclonal Antibody diluted at 1:2000
Western Blot analysis of 293 cells using SH-PTP2 Polyclonal Antibody diluted at 1:2000
Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4°
overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negative control (right) obtaned from antibody was pre-absor
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using SHP-2 Antibody. The picture on the right is blocked with the synthesized peptide.
Immunofluorescence analysis of PC-12 cells using SHP2 at dilution of 1:100 (40x lens).
Blue: DAPI for nuclear staining.