SLUG
| Cat Number: | AB-84208 |
|---|---|
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 89-268 of human SLUG |
| Reactivity: | Hu, Ms, Rt |
| Applications: | Western Blot : 1:500-1:2,000 Immunofluorescence/Immunocytochemistry: 1:50-1: 200 Immunohistochemsitry (paraffin, formalin, frozen Tissues): 1:50-1:200 |
| Molecular: | 29kDa |
| Purification: | Aff. Pur. |
| Synonyms: | SNAI2; SLUG; SLUGH; SLUGH1; SNAIL2; WS2D |
| Background: | This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. |
| Form: | Liquid |
| Buffer: | PBS with 0,02% sodium azide, 50% glycerol pH7.3 |
| Storage: | Storage for short term at 4°C recommended, for longer term at -20°C, minimize freeze/thaw cycles |