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Smad2/3

Cat Number: AB-90212
Size: 100 ug
Clone: POLY
Concentration: 1mg/ml
Host: Rb
Isotype: IgG
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human SMAD3.
Reactivity: Hu, Ms, Rt
Applications: Western Blot: 1:500 - 1:1000 Immunohistochemistry: 1:50 - 1:100 Immunofluorescence: 1:50 - 1:100
Molecular Weight: 56-60kDa
Purification: Aff. Pur.
Synonyms: HSPC193;HsT17436;JV15-2;LDS1C;LDS3;MADH3
Background:

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene ‘mothers against decapentaplegic’ (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factorbeta and is thought to play a role in the regulation of carcinogenesis.

Form: Liquid
Buffer: PBS with 0,02% sodium azide, 50% glycerol pH7.3
Storage: Store at -20℃. Avoid freeze / thaw cycles.