STAT4 Rabbit Monoclonal Antibody
| Cat Number: | MABN83845 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthesized peptide derived from human STAT4 |
| Reactivity: | Human |
| Applications: | WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200,FC 1:20-1:100,IP 1:20-1:50 |
| Molecular: | 86 kDa |
| Purification: | Affinity Purification |
| Synonyms: | Signal transducer and activator of transcription 4; Stat-4; Stat 4;;STAT4 |
| Background: | Transcriptional regulator mainly expressed in hematopoietic cells that plays a critical role in cellular growth, differentiation and immune response .Plays a key role in the differentiation of T-helper 1 cells and the production of interferon-gamma.Participates also in multiple neutrophil functions including chemotaxis and production of the neutrophil extracellular traps (By similarity).After IL12 binding to its receptor IL12RB2, STAT4 interacts with the intracellular domain of IL12RB2 and becomes tyrosine phosphorylated. |
| Form: | Liquid |
| Buffer: | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |