STAT6 Mouse Monoclonal Antibody
| Cat Number: | MABN80861 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | Mouse IgG1 |
| Immunogen: | Purified recombinant fragment of human STAT6 expressed in E. Coli. |
| Reactivity: | Human,Mouse,Rat,Monkey |
| Applications: | WB 1:500-1:2000,ICC 1:200-1:1000,ELISA 1:5000-1:20000 |
| Molecular: | 94kDa |
| Purification: | Affinity Purification |
| Synonyms: | STAT6B; STAT6C; D12S1644; IL-4-STAT; STAT6 |
| Background: | STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL 4 mediated proliferation. STAT6 mRNA has been detected in peripheral bloodlymphocytes, colon, intestine, ovary, prostate,thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. |
| Form: | Liquid |
| Buffer: | Purified antibody in PBS with 0.05% sodium azide. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |