Stromal Interaction Molecule 1 Rabbit Monoclonal Antibody
| Cat Number: | MABN02646 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human Stromal interaction molecule 1 |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:1000 |
| Molecular: | Calculated MW: 77 kDa; Observed MW: 77 kDa |
| Purification: | Affinity Purification |
| Synonyms: | GOK; TAM; TAM1; IMD10; STRMK; D11S4896E |
| Background: | STIM1 is a potential tumor suppressor; defects in STIM1 may cause rhabdomyosarcoma and rhabdoid tumors. STIM1 can either homodimerize or form heterodimers with STIM2. STIM2 possesses a high sequence identity to STIM1 and can function as an inhibitor of STIM1-mediated plasma membrane store-operated Ca2+ entry. However, further investigation is required to elucidate the true physiological function of STIM2. |
| Form: | Liquid |
| Buffer: | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |