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TDP43 Rabbit Polyclonal Antibody

Cat Number: AB-83805
Conjugate: Unconjugated
Size: 100 ug
Clone: POLY
Concentration: 1mg/ml
Host: Rabbit
Isotype: IgG
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300-400 of human TDP-43/TARDB.
Reactivity: Human, Mouse, Rat
Applications: Western Blot: 1:500 - 1:2000 Immunohistochemistry (paraffin-embedded tissues): 1:50 - 1:200 Immunofluorescence: 1:50 - 1:200 Immunocytochemistry: 1:50 - 1:200 ChIP: 1:50 - 1:200
Molecular Weight: 35kDa/45kDa
Purification: Affinity Purified
Synonyms: ALS10; TDP-43; TDP-43/TARDBP
Background:

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present
on chromosome 20.

Form: Liquid
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3..3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.