TDP43 Rabbit Polyclonal Antibody

Cat Number: AB-83805
Conjugate: Unconjugated
Size: 100 ug
Clone: POLY
Concentration: 1mg/ml
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TDP-43
Reactivity: Human, Mouse, Rat

Western Blot 1:500 – 1:2000
Immunoprecipitation 1:50 – 1:100
RNA Immunoprecipitation 1:20 – 1:50

Molecular Weight: 42kDa
Purification: Affinity Purified
Synonyms: ALS10;TDP-43;TARDBP;TDP43

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

Form: Liquid
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage: Store at -20℃. Avoid freeze / thaw cycles.

Western blot analysis of extracts of various cell lines, using TDP43 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.


Immunoprecipitation analysis of 200ug extracts of SW620 cells using 3ug TDP43 antibody. Western blot was performed from the immunoprecipitate using TDP43 antibody at a dilution of 1:500.