TGF beta1 R
| Cat Number: | AB-81203 |
|---|---|
| Size: | 100 ug |
| Clone: | POLY |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Immunogen: | Recombinant protein of human TGFBR1. |
| Reactivity: | Hu,Ms |
| Applications: | Western Blot: 1:500 – 1:2000 |
| Molecular Weight: | 56kDa |
| Purification: | Aff. Pur. |
| Synonyms: | TGFBR1; AAT5; ACVRLK4; ALK-5; ALK5; ESS1; LDS1; LDS1A; LDS2A; MSSE; SKR4; TGFR-1; tbetaR-I;TBRI; TBR-i; TGF-beta receptor type-1 |
| Background: | The protein encoded by this gene forms a heteromeric complex with type II TGFbeta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene |
| Form: | Liquid |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles. |
Western blot analysis of extracts of
various cell lines, using TGFBR1
antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-
Rabbit IgG (H+L) at 1:10000
dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in
TBST.
Detection: ECL Basic Kit.
Exposure time: 30s.
Immunofluorescence analysis of
NIH/3T3 cells using TGFBR1 antibody
at dilution of 1:100. Blue:
DAPI for nuclear staining.