TRAF6 Rabbit Monoclonal Antibody
| Cat Number: | MABN83710 |
|---|---|
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Clone: | Monoclonal |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthesized peptide derived from human TRAF6 |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:1000-1:2000,IHC 1:100-1:200,FC 1:20-1:100 |
| Molecular: | Calculated MW: 60 kDa ; Observed MW: 58 kDa |
| Purification: | Affinity Purification |
| Synonyms: | TNF receptor-associated factor 6; E3 ubiquitin-protein ligase TRAF6; Interleukin-1 signal transducer; RING finger protein 85; TRAF6; RNF85; TRAF 6; TRAF-6;;TRAF6 |
| Background: | E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of ‘Lys-63’-linked-polyubiquitin chains conjugated to proteins, such as ECSIT, IKBKG, IRAK1, AKT1 and AKT2.Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. |
| Form: | Liquid |
| Buffer: | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
| Storage: | Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles. |