4 Hydroxynonenal Rabbit Polyclonal Antibody

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Catalog Number:ABN87884
Conjugate:Unconjugated
Size:100 ul
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:POLY
Immunogen:KLH conjugated 4-Hydroxynonenal
Reactivity:Species-independent
Applications:WB-1:500-1:2000,IHC-1:100-1:500
Purification:Affinity Purification
Form:Liquid

Reactive oxygen and nitrogen species (ROS/RNS) have taken center stage in the field of signal transduction. The enzymes responsible for the production of ROS and RNS have been unraveled and the participation of these species in numerous signaling pathways has been documented. The next step is to identify the targets of ROS and RNS and the mechanisms by which they alter their activity in the affected signaling pathway. This book provides relevant chemistry that can be applied across signaling systems and summarizes the current state of knowledge in the area of redox signaling. ROS and RNS have been implicated in inflammation, aging and cancer.

Applications

WB-1:500-1:2000,IHC-1:100-1:500

Immunogen

KLH conjugated 4-Hydroxynonenal

Target Background

Reactive oxygen and nitrogen species (ROS/RNS) have taken center stage in the field of signal transduction. The enzymes responsible for the production of ROS and RNS have been unraveled and the participation of these species in numerous signaling pathways has been documented. The next step is to identify the targets of ROS and RNS and the mechanisms by which they alter their activity in the affected signaling pathway. This book provides relevant chemistry that can be applied across signaling systems and summarizes the current state of knowledge in the area of redox signaling. ROS and RNS have been implicated in inflammation, aging and cancer.

Storage

Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

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