Immunological Sciences

68kDa Neurofilament Rabbit Monoclonal Antibody

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Catalog Number:MABN86922
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of mouse 68kDa Neurofilament
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:500-1:2000,ICC/IF 1:20-1:50,IP 1:20-1:50
Molecular Weight:Calculated MW:62 kDa; Observed MW:68 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:NFL; NF-L; NF68; CMT1F; CMT2E; PPP1R110

Applications

WB 1:500-1:2000,IHC 1:500-1:2000,ICC/IF 1:20-1:50,IP 1:20-1:50

Immunogen

Recombinant protein of mouse 68kDa Neurofilament

Target Background

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]

Synonyms:NFL; NF-L; NF68; CMT1F; CMT2E; PPP1R110

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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