Immunological Sciences

NQO1 Rabbit Polyclonal Antibody

Western Blot analysis of various cells using NQO1 Polyclonal Antibody diluted at 1:2000

Western Blot analysis of various cells using NQO1 Polyclonal Antibody diluted at 1:2000

Catalog Number:AB-84787
Conjugate:Unconjugated
Size:100 ug
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:POLY
Immunogen:The antiserum was produced against synthesized peptide derived from human NQO1. AA range:203-252
Reactivity:Human, Mouse, Rat
Applications:Western Blot: 1/500 - 1/2000 Immunofluorescence: 1:50-200
Molecular Weight:31kDa
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form:Liquid
Synonyms:NQO1; DIA4; NMOR1; NAD(P)H dehydrogenase [quinone] 1; Azoreductase; DT-diaphorase; DTD; Menadione reductase; NAD(P)H:quinone oxidoreductase 1; Phylloquinone reductase; Quinone reductase 1; QR1

Applications

Western Blot: 1/500 - 1/2000 Immunofluorescence: 1:50-200

Immunogen

The antiserum was produced against synthesized peptide derived from human NQO1. AA range:203-252

Target Background

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms:NQO1; DIA4; NMOR1; NAD(P)H dehydrogenase [quinone] 1; Azoreductase; DT-diaphorase; DTD; Menadione reductase; NAD(P)H:quinone oxidoreductase 1; Phylloquinone reductase; Quinone reductase 1; QR1

Storage

Store at -20℃. Avoid repeated freeze-thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Western Blot analysis of various cells using NQO1 Polyclonal Antibody diluted at 1:2000

Wang, Ting, et al. "Chemopreventive effects of atractylenolide II on mammary tumorigenesis via activating Nrf2-ARE pathway." Oncotarget 8.44 (2017):77500.

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