Immunological Sciences

ABCA6 Rabbit Polyclonal Antibody

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Catalog Number:ABN06396
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthesized peptide derived from ABCA6 . at AA range: 1180-1260
Reactivity:Human,Rat,Mouse
Applications:WB 1:500-1:2000,ELISA 1:20000-1:40000
Molecular Weight:185kDa
Purification:Affinity purification
Form:Liquid
Synonyms:ABCA6; ATP-binding cassette sub-family A member 6

Applications

WB 1:500-1:2000,ELISA 1:20000-1:40000

Immunogen

Synthesized peptide derived from ABCA6 . at AA range: 1180-1260

Target Background

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis. [provided by RefSeq, Jul 2008],developmental stage:Expressed in fetal kidney, lung and liver.,function:Probable transporter which may play a role in macrophage lipid homeostasis.,induction:Up-regulated during monocyte differentiation into macrophages. Down-regulated by cholesterol loading of macrophages.,similarity:Belongs to the ABC transporter family. ABCA subfamily.,similarity:Contains 2 ABC transporter domains.,tissue specificity:Widely expressed with higher expression in liver.,

Synonyms:ABCA6; ATP-binding cassette sub-family A member 6

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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