Acid sphingomyelinase Rabbit Monoclonal Antibody

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Catalog Number:MABN87490
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Acid sphingomyelinase
Reactivity:Human
Applications:WB 1:500-1:2000
Molecular Weight:Calculated MW:70 kDa; Observed MW:70 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ASM; NPD; ASMASE

Applications

WB 1:500-1:2000

Immunogen

Recombinant protein of human Acid sphingomyelinase

Target Background

The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]

Synonyms:ASM; NPD; ASMASE

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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