Immunological Sciences

ADIPOR1 (12R16) Rabbit Monoclonal Antibody

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Catalog Number:MABN06636
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human ADIPOR1
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:20-1:200,ICC/IF 1:50-1:200,FC 1:20-1:200
Molecular Weight:43kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Adiponectin receptor protein 1; Progestin and adipoQ receptor family member I ; CGI-45; PAQR1; ADIPOR1;

Applications

WB 1:1000-1:5000,IHC 1:20-1:200,ICC/IF 1:50-1:200,FC 1:20-1:200

Immunogen

A synthetic peptide of human ADIPOR1

Target Background

Regulate fatty acid oxidation and the uptake of glucose by adiponectin. Each receptor activates a unique set of signaling molecules including AMPK, p38 MAPK and PPAR?. AdipoR1 has a high-affinity for globular adiponectin and low-affinity for full-length adiponectin, while AdipoR2 has an intermediate affinity for both forms. Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:25855295, PubMed:12802337). Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin (By similarity).

Synonyms:Adiponectin receptor protein 1; Progestin and adipoQ receptor family member I ; CGI-45; PAQR1; ADIPOR1;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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